| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 10/12/24 18.45 | FC Girona | FC Liverpool | 0:1 |
| 10/12/24 18.45 | Dinamo Zagabria | Celtic Glasgow | 0:0 |
| 10/12/24 21.00 | Bayer 04 Leverkusen | Inter | 1:0 |
| 10/12/24 21.00 | Shakhtar Donezk | FC Bayern Monaco | 1:5 |
| 10/12/24 21.00 | FC Red Bull Salisburgo | Paris St. Germain | 0:3 |
| 10/12/24 21.00 | Club Brügge | Sporting Lisbona | 2:1 |
| 10/12/24 21.00 | Stade Brest 29 | PSV Eindhoven | 1:0 |
| 10/12/24 21.00 | RB Lipsia | Aston Villa | 2:3 |
| 10/12/24 21.00 | Atalanta | Real Madrid | 2:3 |
| 11/12/24 18.45 | OSC Lille | SK Sturm Graz | 3:2 |
| 11/12/24 18.45 | Atletico Madrid | SK Slovan Bratislava | 3:1 |
| 11/12/24 21.00 | Juventus | Manchester City | 2:0 |
| 11/12/24 21.00 | Benfica Lisbona | Bologna | 0:0 |
| 11/12/24 21.00 | Borussia Dortmund | FC Barcellona | 2:3 |
| 11/12/24 21.00 | Feyenoord Rotterdam | Sparta Praga | 4:2 |
| 11/12/24 21.00 | Milan | Stella Rossa Belgrado | 2:1 |
| 11/12/24 21.00 | FC Arsenal | AS Monaco | 3:0 |
| 11/12/24 21.00 | VfB Stoccarda | Young Boys Berna | 5:1 |